SCHEMBL7923703

SCHEMBL7923703

CCCCCC=Cc1ccccc1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 2/20 0.48
CYSLTR1 Q9Y271 2/20 0.48
F7 P08709 3/20 0.44
F3 P13726 3/20 0.44
MAPT P10636 2/20 0.44
MMP2 P08253 2/20 0.44
LMNA P02545 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ALOX15 P16050 1/20 0.44
ECE1 P42892 1/20 0.44
SGMS1 Q86VZ5 1/20 0.44
SGMS2 Q8NHU3 1/20 0.44
MUS81 Q96NY9 1/20 0.44
HSD17B10 Q99714 1/20 0.44
SAE1 Q9UBE0 1/20 0.44
TRPA1 O75762 1/20 0.44
NFKB1 P19838 2/20 0.43
EPHX2 P34913 1/20 0.43
CDK4 P11802 1/20 0.43
CCND1 P24385 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17666840 1.00 CYSLTR2 (0.48) CYSLTR2CYSLTR1F7F3MAPT
SCHEMBL1001649 0.98 CYSLTR2 (0.50) CYSLTR2CYSLTR1F7F3MAPT
SCHEMBL10743923 0.98 CYSLTR2 (0.50) CYSLTR2CYSLTR1F7F3MAPT
SCHEMBL10752074 0.98 CYSLTR2 (0.50) CYSLTR2CYSLTR1F7F3MAPT
SCHEMBL1001648 0.98 CYSLTR2 (0.50) CYSLTR2CYSLTR1F7F3MAPT
SCHEMBL1072895 0.98 CYSLTR2 (0.50) CYSLTR2CYSLTR1F7F3MAPT
SCHEMBL1277029 0.98 CYSLTR2 (0.50) CYSLTR2CYSLTR1F7F3MAPT
SCHEMBL1072894 0.98 CYSLTR2 (0.50) CYSLTR2CYSLTR1F7F3MAPT
SCHEMBL10750148 0.98 CYSLTR2 (0.50) CYSLTR2CYSLTR1F7F3MAPT
SCHEMBL1277031 0.98 CYSLTR2 (0.50) CYSLTR2CYSLTR1F7F3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3006543-B1 POLYFUNCTIONAL LUBRICANT COMPOSITION ADEKA CORP (JP) 2021-05-26 EP disclosed
US-9738848-B2 Polyfunctional lubricant composition ADEKA CORPORATION (JP) 2017-08-22 US disclosed
US-20160122679-A1 POLYFUNCTIONAL LUBRICANT COMPOSITION ADEKA CORPORATION (JP) 2016-05-05 US disclosed
EP-3006543-A1 POLYFUNCTIONAL LUBRICANT COMPOSITION Adeka Corporation (JP) 2016-04-13 EP disclosed
US-6235923-B1 RETINOIDS AND CELL DIFFERENTIATION ALLERGAN SALES, INC. 2001-05-22 US disclosed
US-6225494-B1 TREATING SKIN DISORDERS, REDUCED SIDE EFFECTS ALLERGAN SALES, INC. 2001-05-01 US disclosed
US-6037488-A COMPOUNDS SUCH AS 4-((4'-ISOPROPOXY-3'-(1-M-TOLYL)VINYL)PHENYLETHYNYL)BENZOIC ACID ALLERGAN SALES, INC. (US) 2000-03-14 US disclosed
EP-0975573-A1 TRISUBSTITUTED PHENYL DERIVATIVES HAVING RETINOID AGONIST, ANTAGONIST OR INVERSE AGONIST TYPE BIOLOGICAL ACTIVITY Allergan Sales, Inc. (US) 2000-02-02 EP disclosed
WO-1998047854-A1 TRISUBSTITUTED PHENYL DERIVATIVES HAVING RETINOID AGONIST, ANTAGONIST OR INVERSE AGONIST TYPE BIOLOGICAL ACTIVITY ALLERGAN SALES, INC. (US) 1998-10-29 WO disclosed