SCHEMBL7923734

SCHEMBL7923734

Oc1ccc2c(O)c3ccccc3c(O)c2c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN22 Q9Y2R2 1/20 0.48
IDO1 P14902 2/20 0.48
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
ALOX15 P16050 2/20 0.41
RECQL P46063 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
THRB P10828 2/20 0.41
APP P05067 1/20 0.41
TSHR P16473 1/20 0.41
CASP1 P29466 1/20 0.41
SNCA P37840 1/20 0.41
LMNA P02545 2/20 0.40
HTT P42858 1/20 0.40
BAD Q92934 1/20 0.39
PTGS2 P35354 1/20 0.39
ALDH1A1 P00352 2/20 0.38
HDAC3 O15379 2/20 0.38
EP300 Q09472 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3991314 0.80 IDO1 (0.52) PTPN22IDO1MAPTHPGDALOX15
SCHEMBL145008 0.79 PIM1 (0.61) PTPN22IDO1MAPTHPGDALOX15
SCHEMBL29635249 0.79 PIM1 (0.61) PTPN22IDO1MAPTHPGDALOX15
SCHEMBL372102 0.77 PIM1 (0.43) PTPN22IDO1MAPTHPGDALOX15
SCHEMBL29986805 0.77 PADI4 (0.44) PTPN22IDO1MAPTHPGDRECQL
SCHEMBL1502477 0.77 PADI4 (0.44) PTPN22IDO1MAPTHPGDRECQL
SCHEMBL526630 0.76 IDO1 (0.56) PTPN22IDO1MAPTHPGDALOX15
SCHEMBL188213 0.74 PTPN22 (0.46) PTPN22IDO1MAPTHPGDALOX15
SCHEMBL29054595 0.74 PTPN22 (0.46) PTPN22IDO1MAPTHPGDALOX15
SCHEMBL29032121 0.73 SRC (0.40) PTPN22IDO1MAPTHPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021057721-A1 SPECIFIC ANTIDOTAL DRUG FOR TREATING PARAQUAT ACUTE POISONING 中国热带农业科学院环境与植物保护研究所 2021-04-01 WO disclosed
EP-0890176-B1 PROTON CONDUCTOR IN LIQUID FORM HYDRO QUEBEC (CA) 2001-06-20 EP disclosed
US-6120696-A MIXTURE OF IMIDAZOLES OR TRIAZOLES OR THEIR POLYMERS WITH THEIR SALTS OF PERFLUOROALKYLSULFONIC OR SULFINIC ACIDS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2000-09-19 US disclosed
EP-0890176-A1 PROTON CONDUCTOR IN LIQUID FORM HYDRO-QUEBEC (CA) 1999-01-13 EP disclosed
WO-1998029877-A1 PROTON CONDUCTOR IN LIQUID FORM HYDRO-QUEBEC (CA) 1998-07-09 WO disclosed