SCHEMBL7925075

SCHEMBL7925075

C#CCC(C(=O)O)C(C)C.C#CCC(C=CC)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
GRIK1 P39086 2/20 0.31
GRIK2 Q13002 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7552295 0.88 GRIK1 (0.37) SLC1A3SLC1A2SLC1A1GRIK1GRIK2
SCHEMBL7554466 0.82 SLC1A3 (0.45) SLC1A3SLC1A2SLC1A1GRIK1GRIK2
SCHEMBL8847128 0.73 GRIK1 (0.34) GRIK1GRIK2
SCHEMBL8847089 0.73 GRIK1 (0.34) GRIK1GRIK2
SCHEMBL8847051 0.71 GRIK1 (0.33) GRIK1GRIK2
SCHEMBL8847050 0.71 GRIK1 (0.33) GRIK1GRIK2
SCHEMBL7424012 0.70 GRIK1 (0.41) SLC1A3SLC1A2SLC1A1GRIK1GRIK2
SCHEMBL7555373 0.70 GRIK1 (0.35) GRIK1GRIK2
SCHEMBL8847222 0.70 GRIK1 (0.35) GRIK1GRIK2
SCHEMBL17212018 0.70 GRIK1 (0.46) SLC1A3SLC1A2SLC1A1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0778820-B1 NEUROTROPHIC AND ANTIPROLIFERATIVE COMPOUNDS AMERICAN BIOGENETIC SCIENCES (US) 2001-05-02 EP claimed