Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8447440 | 0.79 | TSHR (0.31) | TSHR | |
| SCHEMBL8135096 | 0.79 | — | — | |
| SCHEMBL12814498 | 0.79 | TSHR (0.37) | TSHR | |
| SCHEMBL12814743 | 0.77 | — | — | |
| SCHEMBL15915249 | 0.77 | TSHR (0.32) | TSHR | |
| SCHEMBL2352027 | 0.77 | TSHR (0.32) | TSHR | |
| SCHEMBL2340393 | 0.77 | TSHR (0.32) | TSHR | |
| SCHEMBL28461244 | 0.77 | TSHR (0.32) | TSHR | |
| SCHEMBL5089666 | 0.77 | TSHR (0.32) | TSHR | |
| SCHEMBL29199156 | 0.77 | TSHR (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232516-B1 | Process for cyclopentadiene substitution | DSM N.V. (NL) | 2001-05-15 | — | — | US | disclosed |
| US-6124488-A | ACTIVE AS CATALYST COMPONENTS, IN PARTICULAR FOR THE POLYMERIZATION OF OLEFINS. | DSM N.V. (NL) | 2000-09-26 | — | — | US | disclosed |
| US-6072067-A | Cyclopentadiene compound substituted with a hetero atom-containing group | DSM N.V. (NL) | 2000-06-06 | — | — | US | disclosed |
| EP-0805142-B1 | Cyclopentadiene compound substituted with a hetero atom-containing group | DSM NV (NL) | 1999-03-24 | — | — | EP | disclosed |
| EP-0900192-A1 | SYNTHESIS OF AN AMINE-CONTAINING CYCLOPENTADIENE | DSM N.V. (NL) | 1999-03-10 | — | — | EP | disclosed |
| EP-0900195-A1 | CYCLOPENTADIENE COMPOUND SUBSTITUTED WITH BRANCHED ALKYL GROUPS | DSM N.V. (NL) | 1999-03-10 | — | — | EP | disclosed |
| EP-0805133-B1 | Process for cyclopentadiene substitution | DSM NV (NL) | 1998-10-07 | — | — | EP | disclosed |
| WO-1997042162-A1 | CYCLOPENTADIENE COMPOUND SUBSTITUTED WITH BRANCHED ALKYL GROUPS | DSM N.V. (NL) | 1997-11-13 | — | — | WO | disclosed |
| WO-1997042151-A1 | CYCLOPENTADIENE COMPOUND SUBSTITUTED BY CHIRAL GROUPS | DSM N.V. (NL) | 1997-11-13 | — | — | WO | disclosed |
| WO-1997042158-A1 | SYNTHESIS OF A SUBSTITUTED CYCLOPENTADIENE COMPOUND | DSM N.V. (NL) | 1997-11-13 | — | — | WO | disclosed |
| WO-1997042157-A1 | SYNTHESIS OF AN AMINE-CONTAINING CYCLOPENTADIENE | DSM N.V. (NL) | 1997-11-13 | — | — | WO | disclosed |
| EP-0805133-A1 | Process for cyclopentadiene substitution | DSM N.V. (NL) | 1997-11-05 | — | — | EP | disclosed |
| EP-0805142-A1 | Cyclopentadiene compound substituted with a hetero atom-containing group | DSM N.V. (NL) | 1997-11-05 | — | — | EP | disclosed |