Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3953470 | 0.80 | METAP1 (0.38) | METAP1CYP1A2EPHX1SIGMAR1HPGD | |
| SCHEMBL4762810 | 0.79 | EPHX1 (0.34) | CYP1A2EPHX1SIGMAR1SHBG | |
| SCHEMBL3951655 | 0.78 | METAP1 (0.35) | METAP1CYP1A2 | |
| SCHEMBL6057415 | 0.77 | EPHX1 (0.32) | EPHX1SHBG | |
| SCHEMBL8955184 | 0.76 | METAP1 (0.39) | METAP1CYP1A2EPHX1HPGD | |
| SCHEMBL8955167 | 0.76 | METAP1 (0.39) | METAP1CYP1A2EPHX1HPGD | |
| SCHEMBL8955314 | 0.76 | METAP1 (0.39) | METAP1CYP1A2EPHX1HPGD | |
| SCHEMBL28366788 | 0.72 | — | — | |
| SCHEMBL2990994 | 0.72 | METAP1 (0.44) | METAP1CYP1A2EPHX1SIGMAR1HPGD | |
| SCHEMBL2992784 | 0.72 | EPHX1 (0.48) | METAP1CYP1A2EPHX1SIGMAR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790257-B1 | SOLID CATALYTIC COMPONENT AND CATALYST FOR POLYMERIZING OLEFINS | TOHO TITANIUM CO LTD (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-5932510-A | AN OLEFIN POLYMERIZATION CATALYST CONSISTS OF THE REACTION PRODUCT OF DIALKOXYMAGNESIUM OR DIARYLOXYMAGNESIUM, HALOALKOXYTITANIUM OR HALOGENATED TITANIUM, A DIESTER OF PHTHALIC ACID, A CYCLIC OR CHAIN POLYSILOXANE | TOHO TITANIUM CO., LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0790257-A1 | SOLID CATALYTIC COMPONENT AND CATALYST FOR POLYMERIZING OLEFINS | TOHO TITANIUM CO., LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |