Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 5/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25328275 | 1.00 | TSHR (0.57) | TSHRHPGDFAAHLPAR1LPAR2 | |
| SCHEMBL30121599 | 1.00 | TSHR (0.57) | TSHRHPGDFAAHLPAR1LPAR2 | |
| SCHEMBL30258755 | 1.00 | TSHR (0.57) | TSHRHPGDFAAHLPAR1LPAR2 | |
| SCHEMBL30757948 | 1.00 | TSHR (0.57) | TSHRHPGDFAAHLPAR1LPAR2 | |
| SCHEMBL30259226 | 1.00 | TSHR (0.57) | TSHRHPGDFAAHLPAR1LPAR2 | |
| SCHEMBL20158183 | 0.93 | LPAR1 (0.63) | HPGDLPAR1LPAR2ENPP2ALDH1A1 | |
| SCHEMBL31477863 | 0.93 | LPAR1 (0.63) | HPGDLPAR1LPAR2ENPP2ALDH1A1 | |
| SCHEMBL30646054 | 0.92 | TSHR (0.57) | TSHRHPGDFAAHLPAR1LPAR2 | |
| SCHEMBL30960413 | 0.92 | TSHR (0.51) | TSHRHPGDFAAHLPAR1LPAR2 | |
| SCHEMBL23553257 | 0.92 | TSHR (0.51) | TSHRHPGDFAAHLPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245829-B1 | ACRYLATED ESTER | DSM NV (NL) | 2001-06-12 | — | — | US | disclosed |
| EP-0956318-A1 | RADIATION-CURABLE COMPOSITION | DSM N.V. (NL) | 1999-11-17 | — | — | EP | disclosed |
| WO-1998033855-A1 | RADIATION-CURABLE COMPOSITION | DSM N.V. (NL) | 1998-08-06 | — | — | WO | disclosed |