Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.51 |
| ▸ | PPARG | P37231 | 12/20 | 0.46 |
| ▸ | RXRA | P19793 | 8/20 | 0.46 |
| ▸ | RXRB | P28702 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 5/20 | 0.45 |
| ▸ | RXRG | P48443 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | PTGES | O14684 | 4/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4433116 | 0.86 | PPARA (0.57) | PPARAPPARGRXRARXRBPPARD | |
| SCHEMBL8015983 | 0.85 | PPARA (0.57) | PPARAPPARGRXRARXRBPPARD | |
| SCHEMBL3380949 | 0.77 | PPARA (0.67) | PPARAPPARGRXRARXRBPPARD | |
| SCHEMBL3512239 | 0.72 | PPARA (0.69) | PPARAPPARGRXRARXRBPPARD | |
| Pirinixil SCHEMBL8015979 | 0.70 | PPARA (0.62) | PPARAPPARGRXRARXRBPPARD | |
| Pirinixil SCHEMBL2109826 | 0.68 | PPARA (0.74) | PPARAPPARGRXRARXRBPPARD | |
| SCHEMBL11484264 | 0.64 | PPARA (0.74) | PPARAPPARGRXRARXRBPPARD | |
| Acetic Acid SCHEMBL3773388 | 0.64 | PPARA (0.61) | PPARAPPARGRXRARXRBPPARD | |
| Aronixil SCHEMBL2732727 | 0.63 | PPARA (0.64) | PPARAPPARGRXRARXRBPPARD | |
| SCHEMBL11482717 | 0.63 | PPARA (0.71) | PPARAPPARGRXRARXRBPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184215-B1 | TOPICALLY APPLYING TO SKIN A HYDROXYCHOLESTEROL TO ACTIVATE LIVER-BASED X-ACTIVATED RECEPTOR ALPHA (LXRA) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-02-06 | — | — | US | disclosed |