Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14716784 | 1.00 | BACE1 (0.61) | BACE1BACE2 | |
| SCHEMBL9913129 | 1.00 | BACE1 (0.61) | BACE1BACE2 | |
| SCHEMBL1935127 | 0.87 | BACE1 (0.63) | BACE1BACE2 | |
| SCHEMBL7922357 | 0.87 | BACE1 (0.63) | BACE1BACE2 | |
| SCHEMBL18124210 | 0.85 | BACE1 (0.58) | BACE1BACE2 | |
| SCHEMBL7916599 | 0.85 | BACE1 (0.58) | BACE1BACE2 | |
| SCHEMBL2631623 | 0.83 | BACE1 (0.59) | BACE1BACE2 | |
| SCHEMBL2622844 | 0.83 | BACE1 (0.59) | BACE1BACE2 | |
| SCHEMBL11888095 | 0.83 | BACE1 (0.59) | BACE1BACE2 | |
| SCHEMBL2934136 | 0.83 | BACE1 (0.59) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332943-A1 | NOVEL FUSED AMINODIHYDROTHIAZINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010038686-A1 | NOVEL FUSED AMINODIHYDROTHIAZINE DERIVATIVE | エーザイ・アール・アンド・ディー・マネジメント株式会社 (JP) | 2010-04-08 | — | — | WO | disclosed |