Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 7/20 | 0.76 |
| ▸ | BCHE | P06276 | 7/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2401340 | 1.00 | BCHE (0.76) | BCHEACHE | |
| Bromide SCHEMBL7927268 | 1.00 | BCHE (0.76) | BCHEACHE | |
| Bromide SCHEMBL7919286 | 0.98 | BCHE (0.71) | BCHEACHE | |
| SCHEMBL30105291 | 0.98 | BCHE (0.75) | BCHEACHE | |
| SCHEMBL7045560 | 0.98 | BCHE (0.75) | BCHEACHE | |
| SCHEMBL7046057 | 0.98 | BCHE (0.75) | BCHEACHE | |
| SCHEMBL2407838 | 0.98 | BCHE (0.75) | BCHEACHE | |
| Ammonia Solution, Strong SCHEMBL28709118 | 0.95 | BCHE (0.71) | BCHEACHE | |
| SCHEMBL5393053 | 0.95 | BCHE (0.70) | BCHEACHE | |
| Bromide SCHEMBL7928519 | 0.90 | BCHE (0.67) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108714216-A | Chemotherapy-photo-thermal combination therapy cancer compound system of double targeting mediations, preparation method and applications | 吉林大学 | 2018-10-30 | — | — | CN | claimed |
| CN-107648619-A | The composite drug-loaded systems of magnetic crust core MOFs, the preparation method and applications of a kind of post aromatic hydrocarbons nano-valve controlled release | 吉林大学 | 2018-02-02 | — | — | CN | claimed |
| CN-108714216-A | Chemotherapy-photo-thermal combination therapy cancer compound system of double targeting mediations, preparation method and applications | 吉林大学 | 2018-10-30 | — | — | CN | disclosed |
| CN-107648619-A | The composite drug-loaded systems of magnetic crust core MOFs, the preparation method and applications of a kind of post aromatic hydrocarbons nano-valve controlled release | 吉林大学 | 2018-02-02 | — | — | CN | disclosed |
| EP-0830388-A4 | ION EXCHANGE POLYMERS FOR ANION SEPARATIONS | UNIV CALIFORNIA (US) | 2001-03-21 | — | — | EP | disclosed |
| EP-0830388-A1 | ION EXCHANGE POLYMERS FOR ANION SEPARATIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-03-25 | — | — | EP | disclosed |
| EP-0580078-B1 | Hydrophilic groups containing poly(vinylamine) derivatives, process for their manufacture and use thereof as pharmaceutical compounds, substrates for active substances and foodstuff ingredients | HOECHST AG (DE) | 1997-10-15 | — | — | EP | disclosed |
| US-5670550-A | ION EXCHANGING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY TRANSFER (US) | 1997-09-23 | — | — | US | disclosed |
| WO-1996040803-A1 | ION EXCHANGE POLYMERS FOR ANION SEPARATIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-12-19 | — | — | WO | disclosed |
| US-5430110-A | Polyvinylamine derivatives having hydrophilic centers, processes for their preparation and the use of the compounds as a medicament, active compound carrier and foodstuff auxiliary | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-04 | — | — | US | disclosed |
| EP-0580078-A1 | Hydrophilic groups containing poly(vinylamine) derivatives, process for their manufacture and use thereof as pharmaceutical compounds, substrates for active substances and foodstuff ingredients | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-26 | — | — | EP | disclosed |