SCHEMBL7927436

SCHEMBL7927436

CC(C)(C)OC(=O)NC1CCN(Cc2ccccc2)C1=O

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
HDAC1 Q13547 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
SCN9A Q15858 4/20 0.46
NPY1R P25929 2/20 0.46
FPR2 P25090 2/20 0.45
APP P05067 1/20 0.44
NPFFR1 Q9GZQ6 1/20 0.44
NPFFR2 Q9Y5X5 1/20 0.44
KCNA3 P22001 1/20 0.43
SRC P12931 2/20 0.43
STS P08842 1/20 0.43
FKBP1A P62942 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7936884 1.00 KMT2A (0.56) KMT2AL3MBTL1HDAC1HDAC8HDAC6
SCHEMBL6818563 1.00 KMT2A (0.56) KMT2AL3MBTL1HDAC1HDAC8HDAC6
SCHEMBL12527914 0.92 KMT2A (0.55) KMT2AL3MBTL1NPY1RAPPSRC
SCHEMBL12527916 0.91 KMT2A (0.54) KMT2AL3MBTL1NPY1RAPPSRC
SCHEMBL28968936 0.90 SRC (0.48) KMT2AL3MBTL1HDAC1HDAC8HDAC6
SCHEMBL28968940 0.90 SRC (0.48) KMT2AL3MBTL1HDAC1HDAC8HDAC6
SCHEMBL1543088 0.89 TP53 (0.50) KMT2AL3MBTL1FPR2SRC
SCHEMBL31291922 0.88 SCN9A (0.45) KMT2AL3MBTL1SCN9AFPR2SRC
SCHEMBL4760780 0.88 KMT2A (0.43) KMT2AL3MBTL1HDAC1HDAC8HDAC6
SCHEMBL31291853 0.88 SCN9A (0.45) KMT2AL3MBTL1SCN9AFPR2SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025030117-A1 FERROPTOSIS INDUCERS ARPEGGIO BIOSCIENCES, INC. (US) 2025-02-06 WO disclosed
WO-2001017992-A1 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 2001-03-15 WO disclosed