SCHEMBL7927952

SCHEMBL7927952

C[Pd].c1ccc(P(CCCP(c2ccccc2)c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ESR1 P03372 4/20 0.33
ESR2 Q92731 4/20 0.33
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35092 0.92 CYP3A4 (0.45) CYP3A4TDP1ESR1ESR2
Propane SCHEMBL17007613 0.90 TDP1 (0.39) CYP3A4TDP1ESR1ESR2TP53
SCHEMBL31379074 0.90 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2
SCHEMBL4255002 0.90 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2
SCHEMBL28754703 0.90 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2
SCHEMBL954340 0.90 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2
SCHEMBL7934432 0.90 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2
SCHEMBL22749132 0.90 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2
SCHEMBL22749145 0.90 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2
SCHEMBL556980 0.90 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6239250-B1 SINGLE OLEFINS OR COMBINATIONS OF OLEFINS RANGING FROM ETHYLENE TO C12 OLEFINS CAN BE USED TO FORM THE LINEAR ALTERNATING COPOLYMER. AIR PRODUCTS AND CHEMICALS, INC. 2001-05-29 US disclosed
EP-1045017-A1 Hot melt adhesives produced from linear alternating polyketones AIR PRODUCTS AND CHEMICALS, INC. (US) 2000-10-18 EP disclosed