Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 18/20 | 0.74 |
| ▸ | DYRK1A | Q13627 | 12/20 | 0.74 |
| ▸ | DYRK1B | Q9Y463 | 10/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.49 |
| ▸ | CLK2 | P49760 | 4/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10238993 | 0.85 | CLK1 (1.00) | CLK1DYRK1ADYRK1BLMNACLK2 | |
| SCHEMBL10239002 | 0.85 | CLK1 (0.74) | CLK1DYRK1ADYRK1BLMNACLK2 | |
| SCHEMBL24451401 | 0.83 | CLK1 (0.67) | CLK1DYRK1ADYRK1BLMNACLK2 | |
| SCHEMBL11888470 | 0.82 | CLK1 (0.69) | CLK1DYRK1ADYRK1BLMNACLK2 | |
| SCHEMBL20022319 | 0.79 | CLK1 (0.65) | CLK1DYRK1ADYRK1BLMNACLK2 | |
| SCHEMBL3641925 | 0.78 | DYRK1A (0.68) | CLK1DYRK1ADYRK1BHSD17B1 | |
| SCHEMBL29636426 | 0.78 | CLK1 (0.68) | CLK1DYRK1ADYRK1B | |
| SCHEMBL20022297 | 0.78 | CLK1 (0.68) | CLK1DYRK1ADYRK1B | |
| SCHEMBL2012991 | 0.77 | CLK1 (0.63) | CLK1DYRK1ADYRK1BLMNACLK2 | |
| SCHEMBL1391609 | 0.77 | CLK1 (0.69) | CLK1DYRK1ADYRK1BLMNACLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010050445-A1 | BICYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2010-05-06 | — | — | WO | disclosed |