Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.75 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.75 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.64 |
| ▸ | MMP1 | P03956 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115030 | 0.98 | HDAC1 (0.78) | HDAC8HDAC1PDE4BMMP1LMNA | |
| SCHEMBL20653124 | 0.97 | HDAC8 (0.70) | HDAC8HDAC1PDE4BMMP1LMNA | |
| SCHEMBL3171960 | 0.88 | PDE4B (0.79) | HDAC8HDAC1PDE4BMMP1LMNA | |
| SCHEMBL1521117 | 0.86 | HDAC8 (1.00) | HDAC8HDAC1PDE4BMMP1HDAC3 | |
| SCHEMBL3383312 | 0.86 | HDAC8 (1.00) | HDAC8HDAC1PDE4BMMP1HDAC3 | |
| SCHEMBL4082864 | 0.84 | PDE4B (0.86) | HDAC8HDAC1PDE4BMMP1ALDH1A1 | |
| SCHEMBL20653488 | 0.83 | HDAC1 (0.54) | HDAC8HDAC1PDE4BMMP1LMNA | |
| SCHEMBL31063953 | 0.83 | HDAC8 (0.68) | HDAC8HDAC1PDE4BMMP1LMNA | |
| SCHEMBL6160043 | 0.82 | HDAC8 (0.72) | HDAC8HDAC1PDE4BMMP1LMNA | |
| SCHEMBL1521159 | 0.82 | HDAC8 (0.91) | HDAC8HDAC1PDE4BMMP1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039256-A1 | 2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION (US) | 2010-04-08 | — | — | WO | disclosed |