Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 10/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2313550 | 0.88 | IL2 (0.48) | IL2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2314656 | 0.83 | ABCB1 (0.46) | IL2MEN1KMT2A | |
| SCHEMBL13583348 | 0.77 | IL2 (0.42) | IL2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL8239294 | 0.73 | IL2 (0.67) | IL2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL12155635 | 0.73 | IL2 (0.60) | IL2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2819267 | 0.72 | IL2 (0.62) | IL2KMT2ARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL2851676 | 0.72 | IL2 (0.46) | IL2STIM1ORAI1ORAI2 | |
| SCHEMBL8239024 | 0.72 | IL2 (0.54) | IL2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1701956 | 0.72 | STIM1 (0.66) | IL2MEN1KMT2ASTIM1ORAI1 | |
| SCHEMBL452378 | 0.71 | IL2 (0.66) | IL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039237-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2010-04-08 | — | — | WO | disclosed |