Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767641 | 0.82 | KMT2A (0.51) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL29503038 | 0.82 | NPC1 (0.50) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL8502908 | 0.82 | NPC1 (0.50) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL3863254 | 0.81 | KMT2A (0.58) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL13539020 | 0.81 | CA1 (0.52) | NPC1RAB9ATP53HPGDALDH1A1 | |
| SCHEMBL9715716 | 0.80 | KMT2A (0.46) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL11772874 | 0.80 | KMT2A (0.62) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL152563 | 0.80 | MAPT (0.59) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL29603325 | 0.80 | MAPT (0.59) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL9854238 | 0.79 | KMT2A (0.49) | KMT2AMEN1NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033847-A1 | NGAL-BINDING SIDEROPHORES AND USE THEREOF TO TREAT IRON DEFICIENCY AND IRON OVERLOAD | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-03-25 | — | — | WO | disclosed |