Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | SDHB | P21912 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5177944 | 0.93 | CA1 (0.50) | PPARGSDHBCA1CA2CA9 | |
| SCHEMBL4684800 | 0.89 | PTPN1 (0.47) | SDHBCA1CA2CA9PTPN1 | |
| SCHEMBL3679922 | 0.89 | FFAR4 (0.48) | PPARGSDHBCA1CA2CA9 | |
| SCHEMBL5179650 | 0.88 | CA1 (0.50) | PPARGCA1CA2CA9PTPN1 | |
| SCHEMBL5178160 | 0.87 | CA1 (0.56) | PPARGCA1CA2CA9DRD2 | |
| SCHEMBL3670256 | 0.87 | GSTP1 (0.46) | PPARGSDHBCA1CA2CA9 | |
| SCHEMBL13416088 | 0.85 | CA1 (0.45) | SDHBCA1CA2CA9PTPN1 | |
| SCHEMBL3669696 | 0.85 | FFAR4 (0.48) | PPARGSDHBCA1CA2CA9 | |
| Biphenyl SCHEMBL28551760 | 0.85 | CA1 (0.53) | PPARGCA1CA2CA9PTPN1 | |
| SCHEMBL9452745 | 0.84 | CA1 (0.46) | PPARGSDHBCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1138712-A2 | Polyarylene copolymers and proton-conductive membrane | JSR Corporation (JP) | 2001-10-04 | — | — | EP | disclosed |