Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12203754 | 0.90 | KDM4E (0.35) | ERN1AAK1EGFRKDRABL1 | |
| SCHEMBL12203763 | 0.90 | KDM4E (0.35) | ERN1AAK1EGFRKDRABL1 | |
| SCHEMBL7927177 | 0.88 | ERN1 (0.34) | ERN1 | |
| SCHEMBL7920311 | 0.88 | ERN1 (0.34) | ERN1 | |
| SCHEMBL12203484 | 0.84 | ERN1 (0.36) | ERN1KCNH2 | |
| SCHEMBL14134557 | 0.84 | ERN1 (0.36) | ERN1KCNH2 | |
| SCHEMBL12203448 | 0.84 | ERN1 (0.36) | ERN1KCNH2 | |
| SCHEMBL7917660 | 0.83 | CYP1A2 (0.41) | HDAC1HDAC6 | |
| SCHEMBL7924527 | 0.81 | TAAR1 (0.42) | ERN1KCNH2 | |
| SCHEMBL7932270 | 0.81 | TAAR1 (0.42) | ERN1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042473-A1 | BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |