Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917857 | 0.82 | TAAR1 (0.48) | TAAR1ADRA2A | |
| SCHEMBL7927441 | 0.76 | TAAR1 (0.43) | TAAR1ADRA2A | |
| SCHEMBL7917323 | 0.76 | TAAR1 (0.43) | TAAR1ADRA2A | |
| SCHEMBL7929224 | 0.73 | TAAR1 (0.54) | TAAR1ADRA2A | |
| SCHEMBL7917328 | 0.73 | TAAR1 (0.40) | TAAR1ADRA2A | |
| SCHEMBL7917923 | 0.73 | TAAR1 (0.40) | TAAR1ADRA2A | |
| SCHEMBL7924833 | 0.69 | TAAR1 (0.36) | TAAR1ADRA2A | |
| SCHEMBL7924156 | 0.68 | TAAR1 (0.48) | TAAR1ADRA2A | |
| SCHEMBL12229895 | 0.68 | TAAR1 (0.48) | TAAR1ADRA2A | |
| SCHEMBL7918285 | 0.68 | TAAR1 (0.48) | TAAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042473-A1 | BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |