SCHEMBL7929109

SCHEMBL7929109

CCCCCc1cccc(C(F)(F)F)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.61
HDAC1 Q13547 1/20 0.55
HDAC8 Q9BY41 1/20 0.55
TRPV1 Q8NER1 1/20 0.53
HTR2A P28223 2/20 0.53
HTR2B P41595 2/20 0.53
HTR2C P28335 2/20 0.53
LPL P06858 2/20 0.51
LIPG Q9Y5X9 2/20 0.51
MIF P14174 1/20 0.51
SIGMAR1 Q99720 2/20 0.50
IDO1 P14902 2/20 0.50
CYP2D6 P10635 2/20 0.50
ADRA2C P18825 2/20 0.50
SLC6A4 P31645 2/20 0.50
DRD3 P35462 2/20 0.50
TP53 P04637 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
TSHR P16473 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28260251 0.98 TAAR1 (0.59) TAAR1HDAC1HDAC8TRPV1HTR2A
SCHEMBL28261580 0.98 TAAR1 (0.59) TAAR1HDAC1HDAC8TRPV1HTR2A
SCHEMBL2094737 0.98 TAAR1 (0.59) TAAR1HDAC1HDAC8TRPV1HTR2A
SCHEMBL28143319 0.98 TAAR1 (0.59) TAAR1HDAC1HDAC8TRPV1HTR2A
SCHEMBL256694 0.95 TAAR1 (0.62) TAAR1HDAC1HDAC8TRPV1HTR2A
SCHEMBL9351319 0.94 HDAC1 (0.57) TAAR1HDAC1HDAC8TRPV1HTR2A
SCHEMBL30876859 0.87 TAAR1 (0.67) TAAR1HDAC1HDAC8HTR2AHTR2B
SCHEMBL429769 0.87 TAAR1 (0.67) TAAR1HDAC1HDAC8HTR2AHTR2B
Hydrochloric Acid SCHEMBL7988615 0.85 TAAR1 (0.65) TAAR1HDAC1HDAC8HTR2AHTR2B
SCHEMBL27956999 0.84 TAAR1 (0.48) TAAR1HDAC1HDAC8TRPV1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11584852-B2 Compound and colored resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-02-21 US disclosed
EP-3583100-B1 COMPOUNDS CONTAINING SI ATOMS FOR OPTICALLY ACTIVE DEVICES MERCK PATENT GMBH (DE) 2021-05-05 EP disclosed
US-20210002487-A1 COMPOUND AND COLORED RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-01-07 US disclosed
WO-2019163732-A1 COMPOUND AND COLORING RESIN COMPOSITION 住友化学株式会社 2019-08-29 WO disclosed
US-9840481-B2 Allosteric modulators of nicotinic acetylcholine receptors MERCK SHARP & DOHME CORP. (US) 2017-12-12 US disclosed
WO-2017165170-A1 ELECTRON WITHDRAWING GROUP SUBSTITUTED AND MACROCYCLIC PGJ3 ANALOGS AND METHODS OF TREATMENT THEREOF WILLIAM MARSH RICE UNIVERSITY (US) 2017-09-28 WO disclosed
EP-1847533-A1 SIX-MEMBERED HETEROCYCLIC COMPOUND AND THE USE THEREOF Asahi Kasei Pharma Corporation (JP) 2007-10-24 EP disclosed
US-RE37087-E1 1-(4-ETHOXYPHENYL)-4-(4-FLUORO-3-PHENOXYPHENYL)-1 -TRIFLUOROMETHYLBUTANE OR 1-(4-ETHOXY-3-FLUOROPHENYL)-4-(3-PHENOXYPHENYL)-1-TRIFLUOROMETHYLBUTANE, FOR EXAMPLE; COMBATS INSECTS AND MITES SCHERING AKTIENGESELLSCHAFT (DE) 2001-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11584852-B2 Compound and colored resin composition H1-0, HRH3, HRH4 TAAR1 1486/4885HDAC1 1401/4885HDAC8 3164/4885
US-20210002487-A1 COMPOUND AND COLORED RESIN COMPOSITION H1-0, HRH3, HRH4 TAAR1 1486/4885HDAC1 1401/4885HDAC8 3164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.