Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | NMT1 | P30419 | 2/20 | 0.40 |
| ▸ | NMT2 | O60551 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199162 | 0.80 | MAPT (0.51) | MAPTGAASMN1; SMN2TP53MEN1 | |
| SCHEMBL6202376 | 0.79 | MAPK1 (0.50) | MAPTGAASMN1; SMN2TP53MEN1 | |
| SCHEMBL9176964 | 0.77 | MAPT (0.60) | MAPTGAASMN1; SMN2TP53MEN1 | |
| SCHEMBL538115 | 0.77 | NMT1 (0.61) | MAPTGAASMN1; SMN2TP53MEN1 | |
| SCHEMBL6200293 | 0.76 | MAPK1 (0.55) | MAPTGAASMN1; SMN2TP53MEN1 | |
| SCHEMBL1467161 | 0.76 | MAPK1 (0.65) | MAPTGAASMN1; SMN2TP53MEN1 | |
| SCHEMBL11066821 | 0.75 | MEN1 (0.51) | MAPTGAASMN1; SMN2TP53MEN1 | |
| SCHEMBL1616605 | 0.74 | MAPK1 (0.53) | MAPTGAASMN1; SMN2TP53MEN1 | |
| SCHEMBL618410 | 0.74 | MAPT (0.62) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL12850078 | 0.74 | MEN1 (0.50) | MAPTGAAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248739-B1 | DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES | PHARMACIA & UPJOHN COMPANY | 2001-06-19 | — | — | US | disclosed |