⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902342 | 0.72 | — | — | |
| SCHEMBL12806361 | 0.72 | — | — | |
| SCHEMBL12656516 | 0.70 | — | — | |
| SCHEMBL12806483 | 0.69 | NPC1 (0.35) | — | |
| SCHEMBL1685089 | 0.69 | — | — | |
| SCHEMBL13821140 | 0.69 | — | — | |
| SCHEMBL14616083 | 0.69 | — | — | |
| SCHEMBL14479840 | 0.69 | — | — | |
| SCHEMBL13473991 | 0.68 | — | — | |
| SCHEMBL12687509 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380881-B1 | NOVEL BICYCLIC HETEROCYCLIC COMPOUND | SUMITOMO DAINIPPON PHARMA CO LTD (JP) | 2017-01-25 | — | — | EP | disclosed |
| EP-2235014-B1 | BICYCLIC DERIVATIVES OF AZABICYCLIC CARBOXAMIDES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2013-10-09 | — | — | EP | disclosed |
| WO-2012134231-A2 | BENZAMIDE DERIVATIVE AS CANNABINOID RECEPTOR (CB1) ANTAGONIST | 한국화학연구원 (KR) | 2012-10-04 | — | — | WO | disclosed |
| EP-1495018-B3 | TRICYCLIC THROMBIN RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2011-03-16 | — | — | EP | disclosed |
| WO-2010038901-A1 | 7-PIPERIDINOALKYL-3,4-DIHYDROQUINOLONE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-04-08 | — | — | WO | disclosed |
| US-7638546-B1 | Imidazolyl derivatives | IPSEN PHARMA S.A.S. (FR) | 2009-12-29 | — | — | US | disclosed |
| WO-2008005368-A2 | PIPERAZINES AS P2X7 ANTAGONISTS | ABBOTT LABORATORIES (US) | 2008-01-10 | — | — | WO | disclosed |
| US-20070032653-A1 | N-{1-(4-(3-bromophenyl)-1H-imidazol-2-yl)-5-methylhexyl}-N-cyclohexylamine; agonists or antagonists of somatostatin receptors; acromegaly, restenosis, Crohn's disease, systemic sclerosis, external and internal pancreatic pseudocysts and ascites, nesidoblastosis, hyperinsulinism, gastrinoma, etc. | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2007-02-08 | — | — | US | disclosed |