Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.32 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL883187 | 0.78 | NR1H4 (0.34) | SCN9ASCN5ALTC4S | |
| SCHEMBL13559993 | 0.77 | SCN9A (0.31) | SCN9A | |
| SCHEMBL1433015 | 0.77 | SCN9A (0.31) | SCN9A | |
| Hydrochloric Acid SCHEMBL1071386 | 0.77 | NR1H4 (0.34) | SCN9ASCN5ALTC4S | |
| Hydrochloric Acid SCHEMBL2054323 | 0.76 | SCN9A (0.30) | SCN9A | |
| SCHEMBL8206048 | 0.75 | — | — | |
| SCHEMBL13392664 | 0.75 | CA1 (0.34) | MAPTHPGDSCN9ASCN5ALTC4S | |
| SCHEMBL10093258 | 0.74 | CA1 (0.31) | CA1CA2 | |
| SCHEMBL668904 | 0.74 | KMT2A (0.31) | KMT2ALTC4S | |
| SCHEMBL883057 | 0.74 | KMT2A (0.31) | KMT2ALTC4S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036551-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-04-01 | — | — | WO | disclosed |