Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | IL2 | P60568 | 1/20 | 0.43 |
| ▸ | GCK | P35557 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13321611 | 0.88 | MEN1 (0.50) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13640665 | 0.83 | MEN1 (0.56) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7929734 | 0.81 | MEN1 (0.54) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7924572 | 0.80 | MEN1 (0.52) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13838445 | 0.76 | KMT2A (0.51) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15793321 | 0.76 | MEN1 (0.48) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13728275 | 0.76 | MEN1 (0.48) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15793319 | 0.76 | MEN1 (0.48) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7922969 | 0.76 | MEN1 (0.48) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2728441 | 0.74 | NPC1 (0.64) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039237-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2010-04-08 | — | — | WO | disclosed |