Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.73 |
| ▸ | TLR4 | O00206 | 1/20 | 0.66 |
| ▸ | TLR2 | O60603 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793032 | 1.00 | PRMT1 (0.73) | PRMT1TLR4TLR2ALDH1A1LMNA | |
| SCHEMBL27394119 | 1.00 | PRMT1 (0.73) | PRMT1TLR4TLR2ALDH1A1LMNA | |
| SCHEMBL3068651 | 0.86 | PRMT1 (0.74) | PRMT1TLR4TLR2ALDH1A1LMNA | |
| SCHEMBL3068655 | 0.86 | PRMT1 (0.74) | PRMT1TLR4TLR2ALDH1A1LMNA | |
| SCHEMBL1011169 | 0.85 | PRMT1 (1.00) | PRMT1TLR4TLR2ALDH1A1LMNA | |
| SCHEMBL10466720 | 0.85 | PRMT1 (0.72) | PRMT1TLR4TLR2ALDH1A1LMNA | |
| SCHEMBL10466719 | 0.85 | PRMT1 (0.72) | PRMT1TLR4TLR2ALDH1A1LMNA | |
| SCHEMBL1011167 | 0.85 | PRMT1 (1.00) | PRMT1TLR4TLR2ALDH1A1LMNA | |
| SCHEMBL3775942 | 0.83 | PRMT1 (0.70) | PRMT1TLR4TLR2ALDH1A1LMNA | |
| SCHEMBL8321676 | 0.83 | PRMT1 (0.70) | PRMT1TLR4TLR2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104277072-B | A kind of preparation method of (E)-2-aryl vinyl phosphate derivatives | JIANGSU CHINASUN SPECIALTY PRODUCTS CO.,LTD. (CN) | 2016-04-13 | — | — | CN | claimed |
| CN-104277072-A | Method for preparing (E)-2-aryl vinyl phosphonate derivatives | CHINASUN SPECIALTY PRODUCTS CO LTD | 2015-01-14 | — | — | CN | claimed |
| CN-116041241-A | Method for synthesizing pyrrole compound by solid acid catalysis | 浙江工业大学 | 2023-05-02 | — | — | CN | disclosed |
| CN-107188771-B | Chiral synthesis method of gamma-nitrophenol compound | 浙江工业大学 | 2021-08-24 | — | — | CN | disclosed |
| CN-111848678-A | Phosphorus-containing thienopyrimidine derivatives | 正大天晴药业集团股份有限公司 | 2020-10-30 | — | — | CN | disclosed |
| EP-3625222-A1 | PHENYL DERIVATIVES AS PGE2 RECEPTOR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2020-03-25 | — | — | EP | disclosed |
| WO-2018210994-A1 | PHENYL DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2018-11-22 | — | — | WO | disclosed |
| CN-107827774-A | Nitrosamine compound containing two fluoro ethyls and preparation method thereof | 遵义医学院 | 2018-03-23 | — | — | CN | disclosed |
| CN-104277072-B | A kind of preparation method of (E)-2-aryl vinyl phosphate derivatives | JIANGSU CHINASUN SPECIALTY PRODUCTS CO.,LTD. (CN) | 2016-04-13 | — | — | CN | disclosed |
| CN-104059051-B | The preparation method of three substituted-tetrahydro thiophene | SOUTHWEST UNIVERSITY (CN) | 2016-02-03 | — | — | CN | disclosed |
| US-8946260-B2 | 17α-hydroxylase/C17,20-lyase inhibitors | NOVARTIS AG (CH) | 2015-02-03 | — | — | US | disclosed |
| WO-1999057122-A1 | 3-PHENYLPYRROLE ALPHA-1 ADRENERGIC COMPOUNDS | ABBOTT LABORATORIES (US) | 1999-11-11 | — | — | WO | disclosed |
| EP-0923581-A1 | 4-SUBSTITUTED BETA-CARBOLINES AS IMMUNOMODULATORS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1999-06-23 | — | — | EP | disclosed |
| EP-0833630-A4 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | SUGEN INC (US) | 1998-09-02 | — | — | EP | disclosed |
| US-5763470-A | Benzopyran compounds and methods for their use | SUGEN INC. (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0833630-A1 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | Sugen, Inc. (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1998006719-A1 | 4-SUBSTITUTED BETA-CARBOLINES AS IMMUNOMODULATORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1998-02-19 | — | — | WO | disclosed |
| EP-0776324-A1 | ENDOTHELIN ANTAGONISTS | Abbott Laboratories (US) | 1997-06-04 | — | — | EP | disclosed |
| WO-1996040110-A1 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | SUGEN, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996006095-A1 | ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1996-02-29 | — | — | WO | disclosed |