SCHEMBL7930633

SCHEMBL7930633

CCCCOc1c(F)c2c(c(F)c1Nc1c(C)cccc1C)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.38
DHODH Q02127 1/20 0.36
CTSG P08311 3/20 0.36
EGFR P00533 1/20 0.35
PIM1 P11309 1/20 0.35
SLC37A4 O43826 1/20 0.34
CXCR2 P25025 1/20 0.34
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7929873 0.96 ELANE (0.38) ELANEDHODHCTSGEGFRPIM1
SCHEMBL7921360 0.93 MAPK14 (0.36) ELANECTSG
SCHEMBL7921271 0.89 CSNK2A2 (0.42) ELANECXCR2MEN1NPC1ALDH1A1
SCHEMBL7921414 0.89 MAPK14 (0.35) ELANECTSGALDH1A1
SCHEMBL7930686 0.89 ELANE (0.38) ELANECTSGEGFRPIM1SLC37A4
SCHEMBL7928353 0.88 ELANE (0.35) ELANECTSGALDH1A1
SCHEMBL7928355 0.88 ELANE (0.37) ELANECTSGEGFRPIM1MEN1
SCHEMBL7927277 0.87 PTPN1 (0.39) SLC37A4
SCHEMBL7928581 0.85 CSNK2A2 (0.40) ELANECTSGCXCR2MAPTKMT2A
SCHEMBL7930665 0.85 MAPK14 (0.36) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed