SCHEMBL7930807

SCHEMBL7930807

C[Ti](C)(=[SiH2])(OC(=O)c1ccccc1)(OC(=O)c1ccccc1)(C1=CC=CC1)C1=CC=CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
LMNA P02545 2/20 0.38
F2 P00734 1/20 0.38
TDP1 Q9NUW8 4/20 0.37
ALDH1A1 P00352 4/20 0.35
HSD17B10 Q99714 1/20 0.35
TP53 P04637 1/20 0.33
KMT2A Q03164 4/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 2/20 0.33
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.33
POLB P06746 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A3 Q01959 1/20 0.33
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7927389 0.78
SCHEMBL7930345 0.75 MEN1 (0.32) KMT2AMEN1
SCHEMBL7924606 0.74
SCHEMBL7928642 0.73
Benzamide SCHEMBL12486966 0.70 PARP1 (0.50) TSHRLMNATDP1ALDH1A1HSD17B10
SCHEMBL9347744 0.67 TSHR (0.42) TSHRLMNAF2TDP1ALDH1A1
SCHEMBL7924540 0.66
SCHEMBL7931125 0.65 TSHR (0.43) TSHRLMNAF2TDP1ALDH1A1
SCHEMBL7928270 0.65 TSHR (0.43) TSHRLMNAF2TDP1ALDH1A1
Benzoic Acid SCHEMBL7764752 0.64 TSHR (0.48) TSHRALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed