Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RGS4 | P49798 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933454 | 0.98 | NR1H2 (0.47) | NR1H2NR1H3PTPN1PTGS2LIPG | |
| SCHEMBL7934341 | 0.98 | NR1H2 (0.47) | NR1H2NR1H3PTPN1PTGS2LIPG | |
| SCHEMBL7930947 | 0.98 | NR1H2 (0.47) | NR1H2NR1H3PTPN1PTGS2LIPG | |
| SCHEMBL7933477 | 0.98 | NR1H2 (0.47) | NR1H2NR1H3PTPN1PTGS2LIPG | |
| SCHEMBL7936995 | 0.98 | NR1H2 (0.47) | NR1H2NR1H3PTPN1PTGS2LIPG | |
| SCHEMBL7933400 | 0.98 | NR1H2 (0.47) | NR1H2NR1H3PTPN1PTGS2LIPG | |
| SCHEMBL7932652 | 0.98 | NR1H2 (0.47) | NR1H2NR1H3PTPN1PTGS2LIPG | |
| SCHEMBL7933380 | 0.98 | NR1H2 (0.47) | NR1H2NR1H3PTPN1PTGS2LIPG | |
| SCHEMBL7932654 | 0.98 | NR1H2 (0.47) | NR1H2NR1H3PTPN1PTGS2LIPG | |
| SCHEMBL7937030 | 0.98 | NR1H2 (0.47) | NR1H2NR1H3PTPN1PTGS2LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174989-B1 | SYNTHETIC RUBBERS AND VULCANIZATION FOR TIRES | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-01-16 | — | — | US | disclosed |
| US-5981662-A | VULCANIZATES FOR USE IN SIDEWALL, TREAD, CARCASS PLY, WIRECOAT OR OVERLAY COMPOUNDS FOR TIRES; IMPART ANTI-REVERSION AND ANTIFATIGUE PROPERTIES IN THE RUBBER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0908489-A2 | Rubber compounds containing polymeric bis-succinimide polysulfides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-04-14 | — | — | EP | disclosed |