Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 19/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1303705 | 0.89 | PDE10A (1.00) | PDE10A | |
| SCHEMBL1304108 | 0.85 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7937363 | 0.81 | PDE10A (0.66) | PDE10A | |
| SCHEMBL1303704 | 0.81 | PDE10A (0.84) | PDE10A | |
| SCHEMBL1302457 | 0.80 | PDE10A (0.98) | PDE10A | |
| SCHEMBL1303981 | 0.79 | PDE10A (0.65) | PDE10A | |
| SCHEMBL1303469 | 0.79 | PDE10A (1.00) | PDE10A | |
| SCHEMBL1304297 | 0.79 | PDE10A (1.00) | PDE10A | |
| SCHEMBL1303797 | 0.77 | PDE10A (0.82) | PDE10A | |
| SCHEMBL1304113 | 0.77 | PDE10A (0.80) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057121-A1 | PYRAZINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS | AMGEN INC. (US) | 2010-05-20 | — | — | WO | disclosed |