Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931935 | 1.00 | FYN (0.39) | FYNMAOBBACE1EGFRKDM1A | |
| SCHEMBL7929341 | 0.89 | FYN (0.39) | FYNMAOBBACE1KDM1ASMN1; SMN2 | |
| SCHEMBL6473730 | 0.89 | FYN (0.37) | FYNMAOBBACE1EGFRKDM1A | |
| SCHEMBL6473343 | 0.89 | FYN (0.37) | FYNMAOBBACE1EGFRKDM1A | |
| SCHEMBL7929345 | 0.89 | FYN (0.39) | FYNMAOBBACE1KDM1ASMN1; SMN2 | |
| SCHEMBL6479157 | 0.83 | FYN (0.40) | FYNMAOBEGFRKDM1APOLB | |
| SCHEMBL6473346 | 0.81 | FYN (0.37) | FYNMAOBEGFRKDM1A | |
| SCHEMBL6472740 | 0.80 | FYN (0.38) | FYNMAOBBACE1EGFRKDM1A | |
| SCHEMBL7929362 | 0.79 | FYN (0.38) | FYNBACE1EGFRFFAR1FFAR4 | |
| SCHEMBL7929366 | 0.79 | FYN (0.38) | FYNBACE1EGFRFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879814-B1 | Triaromatic compounds, compositions containing them and uses thereof | CT INTERNAT DE BR RECH S DERMA (FR) | 2001-11-28 | — | — | EP | disclosed |
| US-6150413-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, BONE AND OPHTHALMOLOGICAL DISORDERS, AS WELL AS MAMMALIAN SKIN AND HAIR CONDITIONS; 4-(4-(BIPHENYL-2-YL)BUT-3-EN-1-YNYL)BENZOIC ACID, FOR EXAMPLE | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2000-11-21 | — | — | US | disclosed |
| EP-0879814-A1 | Triaromatic compounds, compositions containing them and uses thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-11-25 | — | — | EP | disclosed |