SCHEMBL7932124

SCHEMBL7932124

CCC(c1ccccc1)(c1ccccc1)C(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.44
KCNN4 O15554 4/20 0.43
MAPK1 P28482 1/20 0.42
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
ALDH1A1 P00352 3/20 0.39
ALOX15 P16050 1/20 0.39
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
NR3C2 P08235 1/20 0.36
TSHR P16473 2/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1059140 0.87 KCNN4 (0.48) TAAR1KCNN4MAPK1CYP2C19HIF1A
SCHEMBL11903610 0.83 TAAR1 (0.43) TAAR1KCNN4MAPK1CYP2C19HIF1A
SCHEMBL7950495 0.81 CYP2C19 (0.42) TAAR1KCNN4MAPK1CYP2C19HIF1A
SCHEMBL6740246 0.80 KCNN4 (0.43) TAAR1KCNN4MAPK1CYP2C19HIF1A
SCHEMBL9817084 0.80 KCNN4 (0.43) TAAR1KCNN4MAPK1CYP2C19HIF1A
SCHEMBL6570649 0.78 TAAR1 (0.43) TAAR1KCNN4MAPK1CYP2C19HIF1A
SCHEMBL18419705 0.77 TAAR1 (0.46) TAAR1KCNN4MAPK1CYP2C19HIF1A
SCHEMBL1851360 0.76 CYP2C19 (0.40) TAAR1KCNN4CYP2C19HIF1AALDH1A1
SCHEMBL8815370 0.76 KCNN4 (0.40) TAAR1KCNN4MAPK1CYP2C19HIF1A
SCHEMBL312667 0.76 ESR1 (0.58) ALDH1A1ESR1ESR2CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1123348-A2 IMPACT-RESISTANT EPOXIDE RESIN COMPOSITIONS Henkel Teroson GmbH (DE) 2001-08-16 EP claimed
WO-2000020483-A2 IMPACT-RESISTANT EPOXIDE RESIN COMPOSITIONS HENKEL TEROSON GMBH (DE) 2000-04-13 WO claimed