Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10921526 | 0.92 | GAA (0.43) | GAAKMT2ACDK1TP53NPC1 | |
| SCHEMBL10515589 | 0.92 | HPGD (0.52) | GAAKMT2ACDK1TP53NPC1 | |
| SCHEMBL275841 | 0.90 | TP53 (0.42) | GAAKMT2ATP53NPC1RAB9A | |
| SCHEMBL10618405 | 0.89 | TP53 (0.42) | GAAKMT2ACDK1TP53NPC1 | |
| SCHEMBL8660576 | 0.88 | NPC1 (0.39) | GAAKMT2ATP53NPC1RAB9A | |
| SCHEMBL27681404 | 0.88 | KMT2A (0.38) | GAAKMT2ATP53NPC1RAB9A | |
| SCHEMBL28943274 | 0.88 | HPGD (0.49) | GAAKMT2ATP53NPC1RAB9A | |
| SCHEMBL7798073 | 0.86 | GAA (0.46) | GAAKMT2ACDK1TP53GLA | |
| SCHEMBL10545582 | 0.86 | GAA (0.46) | GAAKMT2ACDK1TP53NPC1 | |
| SCHEMBL10541783 | 0.84 | GAA (0.44) | GAAKMT2ACDK1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235680-B1 | REDUCING SIDE EFFECT OF PESTICIDE | HOECHST SCHERING AGREVO GMBH (DE) | 2001-05-22 | — | — | US | disclosed |