Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.74 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.74 |
| ▸ | EGFR | P00533 | 1/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.74 |
| ▸ | DRD1 | P21728 | 1/20 | 0.74 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.74 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.74 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.74 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.74 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.74 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.74 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.74 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.74 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.74 |
| ▸ | RXRA | P19793 | 5/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932296 | 1.00 | PPARG (0.74) | PPARGCYP1A2MAPTMAPK1PTGS2 | |
| SCHEMBL7932283 | 1.00 | PPARG (0.74) | PPARGCYP1A2MAPTMAPK1PTGS2 | |
| SCHEMBL7920389 | 0.90 | PPARG (0.71) | PPARGCYP1A2MAPTMAPK1PTGS2 | |
| SCHEMBL7920387 | 0.90 | PPARG (0.71) | PPARGCYP1A2MAPTMAPK1PTGS2 | |
| SCHEMBL7920390 | 0.90 | PPARG (0.71) | PPARGCYP1A2MAPTMAPK1PTGS2 | |
| SCHEMBL7926179 | 0.89 | PPARG (0.73) | PPARGCYP1A2MAPTMAPK1PTGS2 | |
| SCHEMBL7926176 | 0.89 | PPARG (0.73) | PPARGCYP1A2MAPTMAPK1PTGS2 | |
| SCHEMBL7926171 | 0.89 | PPARG (0.73) | PPARGCYP1A2MAPTMAPK1PTGS2 | |
| SCHEMBL17826435 | 0.88 | PPARG (0.71) | PPARGCYP1A2MAPTMAPK1PTGS2 | |
| SCHEMBL7920358 | 0.86 | PPARG (0.70) | PPARGCYP1A2MAPTMAPK1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300346-B1 | THERAPY OF PRECANCEROUS LESIONS COMPRISING ADMINISTERING INDENYL HYDROXAMIC ACID DERIVATIVE COMPOUND | CELL PATHWAYS, INC. | 2001-10-09 | — | — | US | disclosed |
| US-6071934-A | PREVENTING TUMORS OR SLOWING THEIR GROWTH | CELL PATHWAYS, INC. (US) | 2000-06-06 | — | — | US | disclosed |
| US-5093356-A | Antiallergens, antiasthma, antiinflammatory, cytoprotective | MERCK FROSST CANADA, INC. (CA) | 1992-03-03 | — | — | US | disclosed |