Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 3/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11685127 | 0.80 | POLB (0.45) | TP53MAPTPOLB | |
| Phosphoric Acid SCHEMBL4636546 | 0.79 | TYR (0.42) | ESR1ESR2ESRRBESRRAHSD17B3 | |
| SCHEMBL6401574 | 0.78 | ESR1 (0.48) | ESR1ESR2EGFRTYRTP53 | |
| SCHEMBL6402444 | 0.78 | ESR1 (0.51) | ESR1ESR2CYP3A4MAPTALOX15 | |
| SCHEMBL6399237 | 0.77 | ESR1 (0.49) | ESR1ESR2CYP3A4MAPTALOX15 | |
| SCHEMBL11801178 | 0.76 | TYR (0.44) | ESR1ESR2HSD17B3TYRMEN1 | |
| SCHEMBL6394292 | 0.75 | SLC28A3 (0.45) | ESR1ESR2EGFRTP53CYP3A4 | |
| SCHEMBL6399258 | 0.75 | IGF1R (0.46) | ESR1ESR2EGFRTP53CYP3A4 | |
| SCHEMBL6395780 | 0.75 | ESR1 (0.38) | ESR1ESR2TSHRPOLB | |
| SCHEMBL6397882 | 0.74 | ESR1 (0.39) | ESR1ESR2EGFRTYRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125984-A1 | Aromatic polycarbonate-styrene polymer resin composition | Asahi Kasei Kabushiki Kaisha (JP) | 2001-08-22 | — | — | EP | disclosed |
| US-6069206-A | COMPATIBILITY AGENT COMPRISING SPECIFIED COPOLYMER OF AROMATIC VINYL MONOMER AND POLYMERIZABLE MONOMER | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2000-05-30 | — | — | US | disclosed |
| US-5900446-A | CONTAINING A COMPATIBILITY AGENT; ADDITION-CONDENSATION COPOLYMER | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1999-05-04 | — | — | US | disclosed |
| EP-0767215-A1 | AROMATIC POLYCARBONATE-STYRENE POLYMER RESIN COMPOSITION | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1997-04-09 | — | — | EP | disclosed |