SCHEMBL7932669

SCHEMBL7932669

C#Cc1ccc(C(=O)O)c2c(C(=O)O)cccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.45
NR4A1 P22736 1/20 0.44
NR4A2 P43354 1/20 0.44
NR4A3 Q92570 1/20 0.44
HSD17B10 Q99714 2/20 0.43
PARP1 P09874 1/20 0.41
ALDH1A1 P00352 5/20 0.40
TSHR P16473 2/20 0.40
ALOX15 P16050 1/20 0.40
TYMS P04818 1/20 0.40
CDC25B P30305 1/20 0.40
FABP7 O15540 1/20 0.38
FABP3 P05413 1/20 0.38
FABP5 Q01469 1/20 0.38
WDR5 P61964 1/20 0.38
PBRM1 Q86U86 1/20 0.37
LDHA P00338 1/20 0.37
KDM4E B2RXH2 3/20 0.37
PRNP P04156 1/20 0.37
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5668811 0.88 NR4A1 (0.47) CYP1A2NR4A1NR4A2NR4A3HSD17B10
SCHEMBL3285789 0.82 CYP1A2 (0.45) CYP1A2NR4A1NR4A2NR4A3HSD17B10
SCHEMBL689207 0.81 NR4A1 (0.52) NR4A1NR4A2NR4A3HSD17B10ALDH1A1
SCHEMBL689124 0.81 NR4A1 (0.47) CYP1A2NR4A1NR4A2NR4A3HSD17B10
SCHEMBL29904701 0.78 NR4A1 (0.61) CYP1A2NR4A1NR4A2NR4A3HSD17B10
SCHEMBL31401789 0.78 NR4A1 (0.61) CYP1A2NR4A1NR4A2NR4A3HSD17B10
SCHEMBL2830679 0.78 NR4A1 (0.61) CYP1A2NR4A1NR4A2NR4A3HSD17B10
SCHEMBL689495 0.76 HSD17B10 (0.58) CYP1A2NR4A1NR4A2NR4A3HSD17B10
SCHEMBL2745521 0.76 NR4A1 (0.46) CYP1A2NR4A1NR4A2NR4A3HSD17B10
SCHEMBL4700698 0.75 HSD17B10 (0.55) CYP1A2NR4A1NR4A2NR4A3HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0834499-B1 Process for the preparation of aromatic vinyl compounds DAINIPPON INK & CHEMICALS (JP) 2001-07-25 EP disclosed
EP-0834499-A1 Process for the preparation of aromatic vinyl compounds DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-04-08 EP disclosed