Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 5/20 | 0.55 |
| ▸ | RARG | P13631 | 8/20 | 0.48 |
| ▸ | RARA | P10276 | 6/20 | 0.48 |
| ▸ | RARB | P10826 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | GOT1 | P17174 | 1/20 | 0.47 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032190 | 0.93 | IKBKB (0.62) | IKBKBRARGRARARARBMEN1 | |
| SCHEMBL7927677 | 0.90 | IKBKB (0.53) | IKBKBRARGRARARARBMEN1 | |
| SCHEMBL7932782 | 0.86 | RARB (0.46) | IKBKBRARGRARARARBMEN1 | |
| SCHEMBL25230655 | 0.85 | IKBKB (0.61) | IKBKBRARGRARARARBMEN1 | |
| SCHEMBL30428692 | 0.85 | IKBKB (0.61) | IKBKBRARGRARARARBMEN1 | |
| SCHEMBL1361023 | 0.84 | IKBKB (0.63) | IKBKBRARGRARARARBMEN1 | |
| SCHEMBL7929428 | 0.83 | IKBKB (0.53) | IKBKBRARGRARARARBMEN1 | |
| SCHEMBL7930000 | 0.82 | IKBKB (0.51) | IKBKBRARGRARARARBMEN1 | |
| SCHEMBL7929568 | 0.82 | IKBKB (0.48) | IKBKBRARGRARARARBMEN1 | |
| SCHEMBL7920621 | 0.82 | IKBKB (0.51) | IKBKBRARGRARARARBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225328-B1 | FOR THERAPY OF DISORDERS OR AILMENTS RELATED TO AN OVERREGULATION OF RETINOIC ACID RECEPTORS AND/OR TO HYPERVIAMINOSIS A | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-05-01 | — | — | US | disclosed |