SCHEMBL7932819

SCHEMBL7932819

CC(N)CN1c2ccccc2Sc2ccccc21

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.69
PTGS2 P35354 2/20 0.69
CYP2D6 P10635 5/20 0.65
CHRM2 P08172 4/20 0.65
HTR1A P08908 4/20 0.65
ADRA2A P08913 4/20 0.65
CHRM1 P11229 4/20 0.65
DRD1 P21728 4/20 0.65
SLC6A2 P23975 4/20 0.65
SLC6A4 P31645 4/20 0.65
ADRA1A P35348 4/20 0.65
OPRM1 P35372 4/20 0.65
DRD3 P35462 4/20 0.65
KCNH2 Q12809 4/20 0.65
ALOX15 P16050 3/20 0.65
HSD17B10 Q99714 3/20 0.65
ALDH1A1 P00352 3/20 0.65
CYP1A2 P05177 3/20 0.65
SLC22A1 O15245 3/20 0.65
LMNA P02545 2/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL11621447 0.98 PTGS1 (0.67) PTGS1PTGS2CYP2D6CHRM2HTR1A
Hydrochloric Acid SCHEMBL11614410 0.98 PTGS1 (0.67) PTGS1PTGS2CYP2D6CHRM2HTR1A
Bromide SCHEMBL11617962 0.98 PTGS1 (0.67) PTGS1PTGS2CYP2D6CHRM2HTR1A
Nitric Acid SCHEMBL11621967 0.88 PTGS1 (0.59) PTGS1PTGS2CYP2D6CHRM2HTR1A
SCHEMBL11612876 0.85 PTGS1 (0.56) PTGS1PTGS2CYP2D6CHRM2HTR1A
SCHEMBL16316914 0.85 PTGS1 (0.73) PTGS1PTGS2CYP2D6CHRM2HTR1A
Ammonia Solution, Strong SCHEMBL11621444 0.81 PTGS1 (0.69) PTGS1PTGS2CYP2D6CHRM2HTR1A
SCHEMBL11687530 0.81 PTGS1 (0.69) PTGS1PTGS2CYP2D6CHRM2HTR1A
SCHEMBL10052734 0.81 PTGS1 (0.69) PTGS1PTGS2CYP2D6CHRM2HTR1A
SCHEMBL31298153 0.81 PTGS1 (1.00) PTGS1PTGS2CYP2D6CHRM2HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115943307-A MR1 ligands and pharmaceutical compositions for immunomodulation 巴塞尔大学 2023-04-07 CN disclosed
EP-2391386-B1 OLIGOMER-PHENOTHIAZINE CONJUGATES NEKTAR THERAPEUTICS (US) 2018-06-27 EP disclosed
WO-2010025135-A2 TRIMEPRAZINE AND ETHOPROPAZINE DERIVATIVES FOR PROMOTING BONE GROWTH OSTEOGENEX INC. (US) 2010-03-04 WO disclosed
US-4183912-A QUATERNARY AMMONIUM PHENOTHIAZINE DERIVATIVES AMERICAN HOME PRODUCTS CORPORATION (US) 1980-01-15 US disclosed
US-4097596-A BRONCHODILATOR AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1978-06-27 US disclosed
US-4029783-A CARDIOTONIC, VASODILATION BOEHRINGER MANNHEIM G.M.B.H. (DT) 1977-06-14 US disclosed
US-3998810-A CARDIAC AND CIRCULATORY ACTIVITY BOEHRINGER MANNHEIM G.M.B.H. (DT) 1976-12-21 US disclosed