SCHEMBL7933025

SCHEMBL7933025

CCc1cccc(C2=C([Zr](C)(C)(=[SiH2])C3=C(c4cccc(CC)c4)C=CC3)CC=C2)c1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 1/20 0.38
BCL2 P10415 1/20 0.36
IDO1 P14902 1/20 0.35
MGLL Q99685 1/20 0.35
NOTUM Q6P988 1/20 0.33
PTGS2 P35354 1/20 0.33
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7938791 0.84 BCL2 (0.38) NISCHBCL2IDO1MGLLNOTUM
Hydrochloric Acid SCHEMBL7933155 0.84 BCL2 (0.35) NISCHBCL2IDO1MGLLPTGS2
Hydrochloric Acid SCHEMBL7926789 0.79 NISCH (0.34) NISCHIDO1ALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL7935865 0.79 BCL2 (0.37) NISCHBCL2IDO1MGLLPTGS2
Hydrochloric Acid SCHEMBL7926800 0.79 BCL2 (0.42) NISCHBCL2IDO1MGLLNOTUM
Hydrochloric Acid SCHEMBL7935710 0.78 TAAR1 (0.33) NISCHPTGS2
Hydrochloric Acid SCHEMBL2401874 0.77
Hydrochloric Acid SCHEMBL28743356 0.75 NISCH (0.40) NISCHBCL2IDO1MGLLNOTUM
Hydrochloric Acid SCHEMBL27519789 0.75 NISCH (0.43) NISCHBCL2IDO1MGLLNOTUM
SCHEMBL11589671 0.75 BCL2 (0.42) NISCHBCL2IDO1MGLLNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184402-B1 RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES CHISSO CORPORATION (JP) 2001-02-06 US disclosed