P-Xylene

P-Xylene

SCHEMBL7933376

Cc1ccc(C)cc1.Cc1cccc2ccccc12

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 6/20 0.85
ALDH1A1 P00352 5/20 0.85
CYP1A2 P05177 8/20 0.64
HSD17B10 Q99714 4/20 0.57
HPGD P15428 3/20 0.57
TSHR P16473 5/20 0.50
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
KMT2A Q03164 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
CYP3A4 P08684 2/20 0.43
MEN1 O00255 1/20 0.43
ACHE P22303 1/20 0.43
KEAP1 Q14145 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3075 0.92 CYP2A6 (1.00) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL10684163 0.92 CYP2A6 (1.00) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL7517852 0.92 CYP2A6 (1.00) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL29903166 0.92 CYP2A6 (1.00) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
O-Xylene SCHEMBL9134944 0.91 CYP2A6 (0.77) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
Hydrochloric Acid SCHEMBL6705962 0.90 CYP2A6 (0.94) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
Ammonia Solution, Strong SCHEMBL7539708 0.90 CYP2A6 (0.94) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
O-Xylene SCHEMBL7050723 0.90 CYP2A6 (0.94) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
Naphthalene SCHEMBL3447588 0.90 CYP2A6 (0.94) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
Ammonia Solution, Strong SCHEMBL21796071 0.90 CYP2A6 (0.94) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6211398-B1 CRUDE NAPHTHALENEDICARBOXYLIC ACID IS ESTERIFIED WITH AN ALKANOL SUCH AS METHANOL TO PRODUCE A CRUDE ESTERIFICATION PRODUCT COMPRISING DIALKYL NAPHTHALENEDICARBOXYLATE AND THE PRODUCT IS PURIFIED BY FLASH DISTILLATION EASTMAN CHEMICAL COMPANY 2001-04-03 US disclosed
EP-1019357-A1 PROCESS FOR THE PURIFICATION OF NAPHTHALENEDICARBOXYLIC ACID EASTMAN CHEMICAL COMPANY (US) 2000-07-19 EP disclosed
WO-1999018062-A1 PROCESS FOR THE PURIFICATION OF NAPHTHALENEDICARBOXYLIC ACID EASTMAN CHEMICAL COMPANY (US) 1999-04-15 WO disclosed