Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.44 |
| ▸ | HTR2C | P28335 | 8/20 | 0.37 |
| ▸ | HTR2A | P28223 | 7/20 | 0.37 |
| ▸ | HTR2B | P41595 | 6/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14255979 | 0.80 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL14255978 | 0.77 | CHRNA7 (0.37) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL5330905 | 0.76 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL14255976 | 0.75 | SLC6A4 (0.61) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL14265356 | 0.75 | SLC6A4 (0.61) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL3611689 | 0.73 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL660942 | 0.73 | CYP2D6 (0.47) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL6220026 | 0.72 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3CYP2D6TAAR1 | |
| SCHEMBL7416026 | 0.69 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL10623387 | 0.68 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144764-A1 | BENZOISOTHIAZOLE AND BENZOISOXAZOLE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS | SUVEN LIFE SCIENCES LIMITED (IN) | 2023-08-03 | — | — | WO | disclosed |
| US-6242448-B1 | Trisubstituted-oxazole derivatives as serotonin ligands | AMERICAN HOME PRODUCTS CORPORATION | 2001-06-05 | — | — | US | disclosed |