Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.43 |
| ▸ | FNTB | P49356 | 2/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 16/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7936010 | 0.83 | FNTA (0.46) | FNTAFNTBPGGT1BSLC6A2SLC6A4 | |
| SCHEMBL7939500 | 0.82 | FNTA (0.41) | FNTAFNTBPGGT1BSLC6A2SLC6A4 | |
| SCHEMBL7933845 | 0.81 | FNTA (0.49) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7933841 | 0.81 | FNTA (0.49) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7937082 | 0.74 | SLC6A4 (0.51) | FNTAFNTBPGGT1BSLC6A2SLC6A4 | |
| SCHEMBL7936119 | 0.74 | SLC6A4 (0.51) | FNTAFNTBPGGT1BSLC6A2SLC6A4 | |
| SCHEMBL7936114 | 0.74 | SLC6A4 (0.51) | FNTAFNTBPGGT1BSLC6A2SLC6A4 | |
| SCHEMBL7933703 | 0.73 | FNTA (0.56) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7933707 | 0.73 | FNTA (0.56) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7939485 | 0.71 | FNTA (0.59) | FNTAFNTBPGGT1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |