Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5193387 | 1.00 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9ACA12 | |
| SCHEMBL7927546 | 1.00 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9ACA12 | |
| Hydrochloric Acid SCHEMBL6385217 | 0.98 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9ACA12 | |
| Hydrochloric Acid SCHEMBL7933721 | 0.98 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9ACA12 | |
| SCHEMBL4572446 | 0.89 | KMT2A (0.47) | MEN1KMT2ANPC1RAB9ACA12 | |
| SCHEMBL12493608 | 0.89 | KMT2A (0.47) | MEN1KMT2ANPC1RAB9ACA12 | |
| Hydrochloric Acid SCHEMBL7062680 | 0.87 | KMT2A (0.46) | MEN1KMT2ANPC1RAB9ACA12 | |
| SCHEMBL12493909 | 0.87 | KMT2A (0.46) | MEN1KMT2ANPC1RAB9ACA12 | |
| SCHEMBL12493905 | 0.87 | KMT2A (0.46) | MEN1KMT2ANPC1RAB9ACA12 | |
| SCHEMBL12493668 | 0.86 | MEN1 (0.44) | MEN1KMT2ANPC1RAB9ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010453-A1 | CHEMOKING RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | WO | disclosed |
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |