Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 16/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL739829 | 0.80 | NOTUM (0.42) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL29427142 | 0.80 | NOTUM (0.42) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL20836150 | 0.78 | NOTUM (0.42) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL31194141 | 0.78 | NOTUM (0.42) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL6971788 | 0.77 | NOTUM (0.39) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL17506246 | 0.77 | NOTUM (0.39) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL30901272 | 0.77 | NOTUM (0.39) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL3945531 | 0.77 | NOTUM (0.39) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL17537336 | 0.77 | NOTUM (0.39) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL3080097 | 0.76 | NOTUM (0.40) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810823-B1 | COMPOSITION FOR CONTROLLING PARASITES | NOVARTIS AG (CH) | 2001-03-14 | — | — | EP | disclosed |
| US-5994395-A | MIXTURE CONTAINING AN ACYLUREA AROMATIC COMPOUND AND ANTIBIOTIC | NOVARTIS ANIMAL HEALTH US, INC. (US) | 1999-11-30 | — | — | US | disclosed |
| EP-0810823-A1 | COMPOSITION FOR CONTROLLING PARASITES | Novartis AG (CH) | 1997-12-10 | — | — | EP | disclosed |
| WO-1996025852-A1 | COMPOSITION FOR CONTROLLING PARASITES | NOVARTIS AG (CH) | 1996-08-29 | — | — | WO | disclosed |