SCHEMBL7933994

SCHEMBL7933994

CC1CCCCCCCCCCCC(O)C(=O)C1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.45
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA4 P22748 2/20 0.41
MMP3 P08254 1/20 0.40
GAA P10253 1/20 0.32
PKM P14618 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
EPHX1 P07099 1/20 0.31
TLR4 O00206 1/20 0.31
NR1I2 O75469 1/20 0.30
KDM4B O94953 1/20 0.30
CHRM1 P11229 1/20 0.30
TBXA2R P21731 1/20 0.30
ADRA1A P35348 1/20 0.30
DOHH Q9BU89 1/20 0.30
CRBN Q96SW2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7191054 1.00 KMT2A (0.45) KMT2ACA1CA2CA4MMP3
SCHEMBL2198065 1.00 KMT2A (0.45) KMT2ACA1CA2CA4MMP3
SCHEMBL2197675 0.89 KMT2A (0.37) KMT2ACA1CA2CA4MMP3
SCHEMBL2197677 0.89 KMT2A (0.37) KMT2ACA1CA2CA4MMP3
SCHEMBL2197669 0.89 KMT2A (0.37) KMT2ACA1CA2CA4MMP3
SCHEMBL11372983 0.88 KMT2A (0.53) KMT2ACA1CA2CA4MMP3
SCHEMBL2195800 0.88 KMT2A (0.42) KMT2ACA1CA2CA4MMP3
SCHEMBL13284055 0.84
SCHEMBL2199031 0.79 KMT2A (0.35) KMT2ACA1CA2CA4
SCHEMBL2199037 0.79 KMT2A (0.35) KMT2ACA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221504-A Preparation method of 14-methyl-2-hydroxy-cyclopentadecanone impurity and reference substance thereof 宏济堂制药(商河)有限公司 2024-06-21 CN claimed
CN-219091160-U 2-hydroxy-14-methyl cyclopentadecanone continuous extraction device 宏济堂制药(商河)有限公司 2023-05-30 CN claimed
CN-118221504-A Preparation method of 14-methyl-2-hydroxy-cyclopentadecanone impurity and reference substance thereof 宏济堂制药(商河)有限公司 2024-06-21 CN disclosed
CN-118221504-A Preparation method of 14-methyl-2-hydroxy-cyclopentadecanone impurity and reference substance thereof 宏济堂制药(商河)有限公司 2024-06-21 CN disclosed
CN-118221504-A Preparation method of 14-methyl-2-hydroxy-cyclopentadecanone impurity and reference substance thereof 宏济堂制药(商河)有限公司 2024-06-21 CN disclosed
CN-219091160-U 2-hydroxy-14-methyl cyclopentadecanone continuous extraction device 宏济堂制药(商河)有限公司 2023-05-30 CN disclosed
CN-219091160-U 2-hydroxy-14-methyl cyclopentadecanone continuous extraction device 宏济堂制药(商河)有限公司 2023-05-30 CN disclosed
CN-219091160-U 2-hydroxy-14-methyl cyclopentadecanone continuous extraction device 宏济堂制药(商河)有限公司 2023-05-30 CN disclosed
EP-1102736-A2 PREPARATION OF MACROCYCLIC KETONES UTILISING ADDITION OF KETONES TO ALKENES QUEST INTERNATIONAL B.V. (NL) 2001-05-30 EP disclosed
EP-0976714-A1 Addition of ketones to alkenes QUEST INTERNATIONAL B.V. (NL) 2000-02-02 EP disclosed
WO-2000001648-A2 PREPARATION OF MACROCYCLIC KETONES UTILISING ADDITION OF KETONES TO ALKENES QUEST INTERNATIONAL B.V. (NL) 2000-01-13 WO disclosed