Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 19/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512648 | 0.93 | PDE4A (0.67) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6512654 | 0.93 | PDE4A (0.67) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL8925196 | 0.87 | PDE4A (0.74) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6509503 | 0.84 | PDE4A (0.59) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6509509 | 0.84 | PDE4A (0.59) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6512242 | 0.80 | PDE4A (0.66) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6512246 | 0.80 | PDE4A (0.66) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6509812 | 0.78 | PDE4A (0.63) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6509817 | 0.78 | PDE4A (0.63) | PDE4APDE4DPDE4BPDE4C | |
| Cdp840 SCHEMBL84490 | 0.76 | PDE4A (1.00) | PDE4APDE4DPDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245774-B1 | ANTIINFLAMMATORY AGENTS; BRONCHODILATOR AGENTS | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-06-12 | — | — | US | claimed |