Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.63 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 7/20 | 0.51 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861333 | 0.91 | CNR1 (0.67) | CNR1CREBBPPOLBL3MBTL1CNR2 | |
| SCHEMBL8793064 | 0.86 | CNR1 (0.68) | CNR1CREBBPPOLBL3MBTL1CNR2 | |
| SCHEMBL9334349 | 0.86 | CNR1 (0.68) | CNR1CREBBPPOLBL3MBTL1CNR2 | |
| SCHEMBL7853735 | 0.86 | CNR1 (0.70) | CNR1CREBBPPOLBL3MBTL1CNR2 | |
| SCHEMBL7924583 | 0.86 | CNR1 (0.58) | CNR1CREBBPPOLBL3MBTL1CNR2 | |
| SCHEMBL8793547 | 0.85 | CNR1 (0.73) | CNR1CREBBPPOLBL3MBTL1CNR2 | |
| SCHEMBL9269935 | 0.85 | CNR1 (0.56) | CNR1CREBBPCNR2LMNA | |
| SCHEMBL8792193 | 0.83 | CNR1 (0.69) | CNR1CREBBPPOLBL3MBTL1CNR2 | |
| SCHEMBL27304797 | 0.83 | CNR1 (0.70) | CNR1CREBBPPOLBL3MBTL1CNR2 | |
| SCHEMBL9267345 | 0.83 | CNR1 (0.57) | CNR1CREBBPPOLBL3MBTL1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242449-B1 | TREATING PROSTATIC HYPERTROPHY, URINATION DISORDERS ASSOCIATED WITH PROSTATIC HYPERTROPHY, MALE PATTERN ALOPECIA, OR ACNE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0997457-A1 | 3-BENZOYLINDOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-05-03 | — | — | EP | disclosed |
| WO-1995023143-A1 | INDOLE DERIVATIVES AS TESTOSTERONE-5-ALPHA-REDUCTASE INHIBITORS | PFIZER LIMITED (GB) | 1995-08-31 | — | — | WO | disclosed |