Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929009 | 0.91 | ESR1 (0.74) | ESR1ESR2 | |
| SCHEMBL7934984 | 0.90 | ESR1 (0.72) | ESR1ESR2 | |
| SCHEMBL7928843 | 0.90 | ESR1 (0.66) | ESR1ESR2 | |
| SCHEMBL13389368 | 0.87 | ESR1 (0.77) | ESR1ESR2 | |
| SCHEMBL8400250 | 0.87 | ESR1 (0.54) | ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL3114483 | 0.87 | ESR1 (0.78) | ESR1ESR2 | |
| SCHEMBL7928814 | 0.86 | ESR1 (0.64) | ESR1ESR2 | |
| SCHEMBL7937042 | 0.86 | ESR1 (0.71) | ESR1ESR2 | |
| SCHEMBL7937061 | 0.85 | ESR1 (0.75) | ESR1ESR2 | |
| SCHEMBL7935119 | 0.84 | ESR1 (0.56) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835868-B1 | 2-Aryl-3-aminoaryloxynaphthyl compounds, intermediates, compositions and methods | LILLY CO ELI (US) | 2001-08-29 | — | — | EP | claimed |
| EP-0835868-A1 | 2-Aryl-3-aminoaryloxynaphthyl compounds, intermediates, compositions and methods | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | claimed |
| EP-0835868-B1 | 2-Aryl-3-aminoaryloxynaphthyl compounds, intermediates, compositions and methods | LILLY CO ELI (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-0835868-A1 | 2-Aryl-3-aminoaryloxynaphthyl compounds, intermediates, compositions and methods | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |