Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K2 | P36507 | 1/20 | 0.53 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432398 | 0.86 | KMT2A (0.49) | MAP2K2MAP2K1STAT3KMT2AKDM4E | |
| SCHEMBL3289292 | 0.85 | STAT3 (0.46) | MAP2K2MAP2K1STAT3KMT2AKDM4E | |
| SCHEMBL4186452 | 0.84 | KMT2A (0.47) | MAP2K2MAP2K1STAT3KMT2AKDM4E | |
| SCHEMBL3291748 | 0.84 | STAT3 (0.44) | MAP2K2MAP2K1STAT3KMT2ABAZ2B | |
| SCHEMBL7115198 | 0.81 | TDP1 (0.55) | MAP2K2MAP2K1STAT3KMT2ABAZ2B | |
| SCHEMBL10517964 | 0.81 | STAT3 (0.53) | MAP2K2MAP2K1STAT3KMT2ABAZ2B | |
| SCHEMBL1045535 | 0.79 | KMT2A (0.43) | MAP2K2MAP2K1STAT3KMT2AKDM4E | |
| SCHEMBL1344957 | 0.79 | STAT3 (0.54) | MAP2K2MAP2K1STAT3KMT2ABAZ2B | |
| SCHEMBL3290754 | 0.78 | KMT2A (0.42) | MAP2K2MAP2K1STAT3KMT2AKDM4E | |
| SCHEMBL3290751 | 0.78 | STAT3 (0.41) | MAP2K2MAP2K1STAT3KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248739-B1 | DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES | PHARMACIA & UPJOHN COMPANY | 2001-06-19 | — | — | US | disclosed |