Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852034 | 0.93 | MEN1 (0.54) | MEN1KMT2AF2LMNAGAA | |
| SCHEMBL6697658 | 0.91 | MEN1 (0.51) | MEN1KMT2AF2LMNAGAA | |
| SCHEMBL6668886 | 0.90 | MEN1 (0.51) | MEN1KMT2AF2LMNAGAA | |
| SCHEMBL6697650 | 0.89 | MEN1 (0.49) | MEN1KMT2AF2LMNAGAA | |
| SCHEMBL6669179 | 0.87 | F2 (0.49) | MEN1KMT2AF2LMNAGAA | |
| SCHEMBL6697748 | 0.86 | KCNH2 (0.58) | MEN1KMT2AF2MAPT | |
| SCHEMBL6693229 | 0.86 | KCNH2 (0.58) | MEN1KMT2AF2MAPT | |
| SCHEMBL6694416 | 0.86 | MEN1 (0.51) | MEN1KMT2AF2LMNAGAA | |
| SCHEMBL6703119 | 0.84 | F2 (0.47) | MEN1KMT2AF2LMNAGAA | |
| SCHEMBL6694747 | 0.83 | MEN1 (0.47) | MEN1KMT2ALMNAGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248739-B1 | DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES | PHARMACIA & UPJOHN COMPANY | 2001-06-19 | — | — | US | disclosed |