SCHEMBL7936116

SCHEMBL7936116

CC1=Cc2ccccc2C1[Zr](C)([SiH2]c1ccccc1)C1C(C)=Cc2ccccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL216535 0.98
SCHEMBL6659310 0.77 CYP19A1 (0.32)
SCHEMBL27492992 0.77 CYP19A1 (0.35)
Hydrochloric Acid SCHEMBL217533 0.76
Hydrochloric Acid SCHEMBL31592075 0.75 CYP19A1 (0.34)
Hydrochloric Acid SCHEMBL7634291 0.73
Hydrochloric Acid SCHEMBL7642828 0.73
Hydrochloric Acid SCHEMBL7007871 0.73
SCHEMBL7602769 0.73 RET (0.31)
SCHEMBL7794022 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6177527-B1 PRECATALYST COMPRISING A MIXTURE OF RACEMIC AND MESO STEREOISOMERS OF A METALLOCENE CATALYST; COCATALYST SELECTED FROM THE GROUP CONSISTING OF TRIS(PERFLUOROPHENYL)BORANE AND ISOBUTYL ALUMOXANE UNION CARBIDE CHEMICAL & PLASTICS TECHNOLOGY CORPORATION 2001-01-23 US disclosed
EP-0992517-A2 A process for the preparation of polyethylene or polypropylene UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2000-04-12 EP disclosed