Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7936374 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL31302733 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL31678548 | 0.89 | — | — | |
| SCHEMBL2965013 | 0.64 | — | — | |
| Bromide SCHEMBL6537317 | 0.61 | — | — | |
| SCHEMBL421917 | 0.61 | — | — | |
| SCHEMBL1325417 | 0.61 | — | — | |
| SCHEMBL23084 | 0.61 | — | — | |
| SCHEMBL23083 | 0.61 | — | — | |
| SCHEMBL852746 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270246-A1 | LINCOSAMIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2025-08-28 | — | — | US | disclosed |
| EP-4511043-A1 | LINCOSAMIDES AND USES THEREOF | President and Fellows of Harvard College (US) | 2025-02-26 | — | — | EP | disclosed |
| WO-2023205206-A1 | LINCOSAMIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-10-26 | — | — | WO | disclosed |
| US-6291713-B1 | TRANSFERRING .ALPHA.,.BETA.-UNSATURATED ALKYL GROUPS TO ELECTROPHILE BY MEANS OF MASKED ZINC ALKYL IN PRESENCE OF APROTIC SOLVENT | METALLGESELLSCHAFT AKTIENGESELLSCHAFT (DE) | 2001-09-18 | — | — | US | disclosed |